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Digital Microfluidic Vitrification of Embryos
Cryopreservation is a key technology in biology and clinical practice. This video shows a digital microfluidic device that automates sample preparation for mammalian embryo vitrification. Individual micro droplets manipulated on the microfluidic device were used as micro-vessels to transport a single mouse embryo through a complete vitrification procedure. Advantages of this approach, compared to manual operation and channel-based microfluidic vitrification, include automated operation, cryoprotectant concentration gradient generation, and feasibility of loading and retrieval of embryos. For details, refer to [J112] on the Publications page.
Decreased Deformability of Lymphocytes in Leukemia
This video shows the measurement of stiffness/deformability changes of lymphocytes in chronic lymphocytic leukemia (CLL) patients, demonstrating that at the single cell level, leukemic metastasis progresses are accompanied by biophysical property alterations. A microfluidic device was utilized to electrically measure cell volume and transit time of single lymphocytes from healthy and CLL patients. The results from testing thousands of cells reveal that lymphocytes from CLL patients have higher stiffness (i.e., lower deformability). For details, refer to [J115] on the Publications page.
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Recent Events

X. Wang's Science Robotics paper and M. Zhu's Nature Communications paper were accepted for publication. (03/2019)

NSERC CREATE Heathcare Robotics (HeRo) was granted by NSERC. (02/2019)

Lab rennovation, funded by Canada foundation for innovation (CFI), was completed. (01/2019)

Y. Sun was elected Fellow of the National Academy of Inventors (NAI). (12/2018)

AMNL presented three papers at MicroTAS'2018 in Kaohsiung, Taiwan. (11/2018)

Y. Sun gave an invited seminar in the Schaefer School of Engineering & Science at Stevens Institute of Technology. (10/2018)

C.H. Cao headed to MIT for his postdoctoral research. AMNL team wishes him the best. (09/2018)

W.K. Dou received a pretigious Ph.D. fellowship from the Ted Rogers Centre for Heart Research Education Fund. (08/2018)

AMNL won the Best Application Paper Award at the International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS) in Nagoya, Japan. (07/2018)

Y. Sun accepted the role of Editor for the Elsevier journal, Sensors & Acutators A: Physical. (06/2018)

AMNL presented three papers at IEEE International Conf. Robotics and Automation (ICRA) in Brisbane, Australia. (05/2018)

J.H. Law won the Ontario Trillium Scholarship; G.Q. Shan won the Connaught International Scholarship; Y. Sun gave an invited seminar at the Univerity of Pennsylvania. (04/2018)

AMNL won the IEEE Transactions on Automation Science and Engineering Best New Application Paper Award. (03/2018)

C. Cao won an NSERC postdoctoral fellowship. His paper in Science Advances was accepted for publication. (02/2018)

AMNL won the UofT Connaught Innovation Award; H.J. Liu won the UPenn postdoctoral fellowship. (01/2018)

Y. Sun gave a plenary talk at IEEE Nanomedicine. (12/2017)

Dr. Peter Kim from National Children's Hospital in D.C. and Prof. Rob Wood from Harvard University visited AMNL. (10&11/2017)

Y. Sun introduced UofT Robotics to a Taiwan delegation headed by the minister of science and technology. (10/2017)

Prof. X.Y. Liu, our previous group member, joined UofT as an associate professor. (09/2017)

L. Wang received, for a second time, a pretigious postdoctoral fellowship from the Ted Rogers Centre for Heart Research Education Fund. (08/2017)

Y. Sun gave invited/keynote talks at Tsinghua University in Beijing, at 2017 Microsystems and Nanoengineering Summit in Dalian, and at MARSS'2017 in Montreal. (07/2017)

AMNL presented five papers at Transducers'17 in Taiwan. (06/2017)

AMNL presented three papers at IEEE ICRA in Singapore. (05/2017)

Event archives [more...]