TY - JOUR T1 - Microfluidic approaches for gene delivery and gene therapy A1 - Kim, Jungkyu A1 - Hwang, Inseong A1 - Britain, Derek A1 - Chung, Taek Dong A1 - Sun, Yu A1 - Kim, Deok-Ho Y1 - 2011 SP - 3941 EP - 3948 JF - Lab on a Chip JO - Lab Chip VL - 11 IS - 23 PB - The Royal Society of Chemistry SN - 1473-0197 UR - http://dx.doi.org/10.1039/C1LC20766K N2 - Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimization of multiple processes and techniques used in gene transfection and the production of gene and drug transporters. Traditional non-viral gene transfection methods, such as electroporation, microinjection and optical gene transfection, are improved from the use of innovative microfluidic systems. Additionally, microfluidic systems have also made the production of many viral and non-viral vectors controlled, automated, and reproducible. In summary, the development and application of microfluidic systems are producing increased efficiency in gene delivery and promise improved gene therapy results. ER -